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Managing HIT with Orgaran

Once switched from heparin to Orgaran, a patient's platelet count may rise rapidly, however²⁵:


• a risk of thrombotic complications remain for approximately 5-6 weeks due to the presence of HIT antibodies therefore:



• prolonged parenteral anticoagulation may be required.


Orgaran is an anticoagulant, similar in structure to heparin. Orgaran can be used as a substitute to heparin in patients those who have a previous history of HIT who require treatment for thrombotic disorders²⁴.

If you think HIT, think Orgaran


• Orgaran should be administered intravenously for the treatment of HIT²⁶.



• Once in use, only individuals over the weight of 90kg need routine monitoring (amidolytic assay is recommended)²⁶.



• Orgaran is recommended by the American College of Chest Physicians (ACCP grade 1B) as an alternative antithrombotic in isolated HIT¹⁸.(see table 1 below for dosing schedule)

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