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Key facts about the treatment of HIT



  • When the diagnosis of HIT is suspected heparin should be discontinued immediately. This includes heparin found in pressure-monitoring lines and intravenous flush solutions18,19.


  • There is an extremely high risk of thrombosis and most patients will develop an associated new or progressive thrombotic event17.


  • Immediate substitution with a safe and effective alternative non-heparin anticoagulant at full dosage is recommended18.


  • A retrospective cohort study suggested that, in patients with serologically confirmed HIT with isolated thrombocytopenia alone managed by either discontinuation of heparin or initiation or continuation of Vitamin K Antagonist (VKA) therapy, the 30-day thrombotic event rate was approximately 50%5.
HIT. Click to enlarge

Contact information

Organon Laboratories Ltd
Cambridge Science Park
Milton Road
Cambridge
CB4 0FL
Telephone 01223 432700
Fax 01223 424368
(www.organon.co.uk)


© 2008 Organon Laboratories. All rights reserved. Date of prep. November 2008. Item code: 09847G