Key facts about the treatment of HIT
- When the diagnosis of HIT is suspected heparin should be discontinued immediately. This includes heparin found in pressure-monitoring lines and intravenous flush solutions18,19.
- There is an extremely high risk of thrombosis and most patients will develop an associated new or progressive thrombotic event17.
- Immediate substitution with a safe and effective alternative non-heparin anticoagulant at full dosage is recommended18.
- A retrospective cohort study suggested that, in patients with serologically confirmed HIT with isolated thrombocytopenia alone managed by either discontinuation of heparin or initiation or continuation of Vitamin K Antagonist (VKA) therapy, the 30-day thrombotic event rate was approximately 50%5.
Contact information
Organon Laboratories Ltd
Cambridge Science Park
Milton Road
Cambridge
CB4 0FL
Telephone 01223 432700
Fax 01223 424368
(www.organon.co.uk)
Cambridge Science Park
Milton Road
Cambridge
CB4 0FL
Telephone 01223 432700
Fax 01223 424368
(www.organon.co.uk)
© 2008 Organon Laboratories. All rights reserved. Date of prep. November 2008. Item code: 09847G


